陈瑛;林守清;魏扬;高洪莲;王绍海;乌正赉;陈蓉;

• 1:首都医科大学附属北京友谊医院妇产科
• 2:中国医学科学院北京协和医学院北京协和医院妇产科
• 3:北京世纪坛医院妇产科
• 4:滨州医学院附属医院临床医学实验中心

摘要(Abstract)：

目的评估绝经过程、年龄和其他相关因素对北京市社区妇女生活质量的影响。方法招募北京市某社区35⁶4岁健康女性,运用中国版绝经期特异性生活质量量表(Menopause-Specific Quality of Life Questionnaire,MENQOL)问卷获取数据。妇女按年龄每5岁分成一组,并同时分为生育期、绝经过渡期和绝经后期,以评价绝经状态和年龄及其他相关因素对生活质量的影响,并分析不同绝经状态之间生活质量的差异。结果在同一年龄段,生活质量从生育期、绝经过渡期到绝经后期呈逐步下降趋势。在绝经过渡期和绝经后期妇女中,血管舒缩症状和躯体领域的生活质量下降显著;绝经后期妇女的心理和性领域生活质量下降显著。随着绝经的进展,性领域的生活质量逐渐下降,但绝经后期早期血管、心理和躯体三方面的生活质量均最差。年龄与血管舒缩领域、性领域生活质量均呈负相关(标准参数分别为0.12、0.19,P均<0.01)。评价自我健康状态为一般或较差的妇女生活质量差于自我评价健康状态为好的妇女(P<0.05)。体重指数高的妇女血管舒缩症状更严重(P<0.05)。结论绝经是对北京社区妇女的生活质量产生负面影响的独立因素,妇女的生活质量随着绝经的到来发生某些规律性的改变。也应考虑年龄和其他因素对生活质量的影响。

关键词(KeyWords)： 社区妇女;绝经;生活质量

Abstract:

Keywords:

基金项目(Foundation):

作者(Authors): 陈瑛;林守清;魏扬;高洪莲;王绍海;乌正赉;陈蓉;

参考文献(References)：

• [1]Blumel JE,Castelo-Branco C,Binfa L,et al.Quality of life after the menopause:a population study[J].Maturitas,2000,34:17-23.
• [2]Fuh JL,Wang SJ,Lee SR,et al.Quality of life and menopausal transition for middle-aged women on Kinmmen Island[J].Qual Life Res,2003,12:53-61.
• [3]Sevgi E,Alatas A,Zencir M.Women's quality of life in the premeno pausal and postmenopausal period[J].Qual Life Res,2005,14:1795-1801.
• [4]Dennerstein L,Dudley E,Guthrie J,et al.Life satisfaction,symptoms and the menopausal transition[J].Medscape Womens Health,2000,5:E4.
• [5]Ekstrom H,Hovelius B.Quality of life and hormone therapy in women before and after menopause[J].Scand J Prim Health Care,2000,18:115-121.
• [6]Yang HY,Cheng FP,Wang XY,et al.On clinical application and assessment of Menopause-Specific Quality of Life Questionnaire(Chinese version)[J].Chin J Epidemiol,2005,26:47-50.
• [7]Soules MR,Sherman S,Parrott E,et al.Executive summary:Stages of Reproductive Aging Workshop(STRAW)[J].Fertil Steril,2001,76:874-878.
• [8]Hilditch JR,Lewis J,Peter A,et al.A menopause-specific quality of life questionnaire:development and psychometric properties[J].Maturitas,1996,24:161-175.
• [9]杨姣,任玉嘉,刘民辉,等.绝经期生存质量量表中文版的标准关联效度研究[J].中南大学学报:医学版,2014,39:727-732.
• [10]Fallahzadeh H.Quality of life after the menopause in Iran:a population study[J].Qual Life Res,2010,19:813-819.
• [11]Jenabi E,Shobeiri F,Hazavehei SM,et al.Assessment of Questionnaire Measuring Quality of Life in Menopausal Women:A Systematic Review[J].Oman Med J,2015,30:151-156.
• [12]Li S,Holm K,Gulanick M,et al.Perimenopause and the quality of life[J].Clin Nurs Res,2000,9:6-26.
• [13]Sukwatana P,Meekhangvan J,Tamrongterakul T,et al.Menopause related symptoms among Thai women in Bangkok[J].Maturitas,1991,13:217-218.
• [14]Boulet MJ,Oddens BJ,Lehert P,et al.Climacteric and menopause in seven South-east Asian countries[J].Maturitas,1994,19:157-176.
• [15]Brown WJ,Mishra GD,Dobson A.Changes in physical symptoms during the menopause transition[J].Int J Behav Med,2002,9:53-67.
• [16]Matthews KA,Wing RR,Kuller LH,et al.Influence of the perimenopause on cardiovascular risk factors and symptoms of middle-aged healthy women[J].Arch Intern Med,1994,154:2349-2355.
• [17]Avis NE,Ory M,Matthews KA,et al.Health-related quality of life in a multiethnic sample of middle-aged women[J].Med Care,2003,41:1262-1276.
• [18]Avis NE,Assmann SF,Kravitz HM,et al.Quality of life in diverse groups of midlife women:assessing the influence of menopause,health status and psychosocial and demographic factors[J].Qual Life Res,2004,13:933-946.
• [19]Li C,Wilawan K,Samsioe G,et al.Health profile of middle-aged women:the Women's Health in the Lund Area(WHILA)study[J].Hum Reprod,2002,17:1379-1385.
• [20]Kwak EK,Park HS,Kang NM.Menopause Knowledge,Attitude,Symptom and Management among Midlife Employed Women[J].J Menopausal Med,2014,20:118-125.
• [21].Punyahotra S,Dennerstein L,Lehert P.Menopausal experience of Thai women.Part 1:symptoms and their correlates[J].Maturitas,1997;26:1-7.
• [22]Gharaibeh M,Al-Obeisat S,Hattab J.Severity of menopausal symptoms of Jordanian women[J].Climacteric,2010;13:385-394.
• [23]Chedraui P,Hidalgo L,Chavez D,et al.Quality of life among postmenopausal Ecuadorian women participating in a metabolic syndrome screening program[J].Maturitas,2007,56:45-53.
• [24]Khan SA,Pace JE,Cox ML,et al.Climacteric symptoms in healthy middle-aged women[J].Br J Clin Pract,1994,48:240-242.
• [25]North American Menopause Society.Estrogen and progestogen use in postmenopausal women:2010 position statement of The North American Menopause Society[J].Menopause,2010,17:242-255.
• [26]Harlow SD,Gass M,Hall JE,et al.Executive summary of the Stages of Reproductive Aging Workshop+10:addressing the unfinished agenda of staging reproductive aging[J].JClin Endocrinol Metab,2012,97:1159-1168.
• [27]Bener A,Falah A.A measurement-specific quality-of-life satisfaction during premenopause,perimenopause and postmenopause in Arabian Qatari women[J].J Midlife Health,2014,5:126-134.
• [28]Sowers MF,Pope S,Welch G,et al.The association of menopause and physical functioning in women at midlife[J].JAm Geriatr Soc,2001,49:1485-1492.
• [29]Gold EB,Block G,Crawford S,et al.Lifestyle and demographic factors in relation to vasomotor symptoms:baseline results from the Study of Women's Health Across the Nation[J].Am J Epidemiol,2004,159:1189-1199.
• [30]Freeman EW,Sammel MD,Grisos JA,et al.Hot flashes in the late reproductive years:risk factors for African American and Caucasian women[J].J Womens Health Gend Based Med,2001,10:67-76.
• [31]Freedman RR.Core body temperature variation in symptomatic and asymptomatic postmenopausal women:brief report[J].Menopause,2002,9:399-401.
• [32]Schwarz S,Vlzke H,Alte D,et al.Menopause and determinants of quality of life in women at midlife and beyond:the Study of Health in Pomerania(SHIP)[J].Menopause,2007,14:123-134.
• [33]Elavsky Sff,Mc Auley E.Physical activity,symptoms,esteem,and life satisfaction during menopause[J].Maturitas,2005,52:374-385.
• [34]Katainen RE,Siirtola TJ,Engblom JR,et al.A populationbased survey of quality of life in middle-aged Finnish women[J].Menopause,2015,22:402-413.