协和医学杂志

2019, v.10(06) 685-691

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如何应对指南制订中的利益冲突
How to Address Conflicts of Interest in Clinical Practice Guidelines

陈耀龙;王健健;詹思延;孙剑;靳英辉;李慧;商洪才;杨克虎;
CHEN Yao-long;WANG Jian-jian;ZHAN Si-yan;SUN Jian;JIN Ying-hui;LI Hui;SHANG Hong-cai;YANG Ke-hu;Evidence-based Medicine Center,School of Basic Medical Sciences,Lanzhou University;WHO Collaborating Center for Guideline Implementation and Knowledge Translation;Chinese GRADE Center;School of Public Health,Lanzhou University;Department of Epidemiology and Biostatistics,Peking University School of Public Health;Hepatology Unit,Nanfang Hospital,Southern Medical University;Center for Evidence-Based and

摘要(Abstract):

利益冲突是影响指南制订客观性、独立性和可靠性的重要因素,如何声明和管理利益冲突是指南制订者、使用者和研究者关注的焦点。本文分析比较了国内外指南制订的主要组织和机构对利益冲突的定义、分类及管理办法,在此基础上,就我国如何更好应对指南制订中的利益冲突提出思考与建议。
Conflicts of interest can affect the credibility,independence,and quality of clinical practice guidelines. Guideline developers,users,and researchers are trying to manage and reduce conflicts of interest worldwide. In this article,we analyzed and compared the definition,classification,and management strategies of conflicts of interest of the key national and international guideline developers,and give recommendations on how to address conflicts of interest in clinical practice guidelines in China.

关键词(KeyWords): 循证医学;临床实践指南;利益冲突
evidence-based medicine;clinical practice guideline;conflicts of interest

Abstract:

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基金项目(Foundation): 国家重点研发计划(2018YFC1705500)

作者(Author): 陈耀龙;王健健;詹思延;孙剑;靳英辉;李慧;商洪才;杨克虎;
CHEN Yao-long;WANG Jian-jian;ZHAN Si-yan;SUN Jian;JIN Ying-hui;LI Hui;SHANG Hong-cai;YANG Ke-hu;Evidence-based Medicine Center,School of Basic Medical Sciences,Lanzhou University;WHO Collaborating Center for Guideline Implementation and Knowledge Translation;Chinese GRADE Center;School of Public Health,Lanzhou University;Department of Epidemiology and Biostatistics,Peking University School of Public Health;Hepatology Unit,Nanfang Hospital,Southern Medical University;Center for Evidence-Based and

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