协和医学杂志

2012, (01)

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肠道贝赫切特综合症的临床病理
Clinical Pathological Performance of Intestinal Behcet’s Disease

梁智勇;刘彤华;王维斌;肖雨;周炜洵

摘要(Abstract):

目的 观察肠道白塞病的临床病理学表现,建立肠道白塞病初步的病理诊断标准。 方法 采用传统组织病理学观察方法,对于北京协和医院收治的行回结肠切除术的2例肠道白塞病病例进行标本肉眼观察及苏木素-伊红染色切片显微镜下观察。结果 两例共同的临床病理特点有:(1)均符合国际公认的白塞病诊断标准;(2)均由于难治性肠道出血行手术切除;(3)肠道溃疡均位于回盲部,多发性,垂直于肠腔长轴,溃疡周围粘膜水肿;(4)在显微镜下均可观察到溃疡下方的非坏死性小血管炎。结论 肠道白塞病的诊断需要在系统性白塞病确诊或高度可疑的情况下除外了其他疾病后,在结合典型的结肠镜和显微镜下表现得出的。
Objective To observe the clinical pathological feature of intestinal Behcet’s disease and to create the basis of pathological standard of intestinal Behcet’s disease. Methods To research the two cases of Ileocolonic resection in Peking Union Medical College Hospital with naked eyes and microscope. Result The same clinical pathological features in the two cases are (1) Meet the internationally accepted diagnostic criteria for Behcet's disease, (2) Ileocolonic resection due to refractory intestinal bleeding, (3) the intestinal ulcers are within the ileocecal junction, multifocal, perpendicular to the long axis of the intestine and with mucosa nearby swollen , (4) There are non-necrotizing vasculitis beneath the ulcers under microscope. Conclusion After making a clinical diagnosis of Intestinal Behcet’s disease or highly suspicious for intestinal Behcet disease and excluding the other disease, the proper diagnosis can be made with the proper performance of colonoscopy and microscope.

关键词(KeyWords): |肠道白塞病|炎性肠病|病理诊断|
|intestinal Behcet’s disease| inflammatory bowel disease| pathological diagnosis|

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作者(Author): 梁智勇;刘彤华;王维斌;肖雨;周炜洵

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