协和医学杂志

2014, v.5(02) 184-188

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固定铅门尺寸技术在宫颈癌容积调强计划设计中的应用
Fixed-jaw Technique in Volumetric Modulated Arc Therapy Plan for Cervical Cancer Radiotherapy

庞廷田;杨波;刘楠;刘峡;邱杰;张福泉;
PANG Ting-tian;YANG Bo;LIU Nan;LIU Xia;QIU Jie;ZHANG Fu-quan;Department of Radiation Oncology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College;

摘要(Abstract):

目的探讨宫颈癌术后患者容积调强计划设计中靶区横向宽度与最优X方向铅门大小之间的关系。方法分别对12例宫颈癌术后患者CT图像制作不同X方向铅门大小的容积调强计划,通过对同一患者的不同计划进行剂量学比较,找到其最优X方向铅门大小。最后通过不同患者靶区体积与最优铅门大小的关系,拟合关于靶区横向宽度与最优铅门大小的函数方程。结果在宫颈癌容积调强计划设计时,随着靶区横向宽度的变化,得到的最优铅门大小也随之改变。通过对不同靶区体积进行变化铅门的容积调强计划设计并比较分析,得到靶区横向宽度(x)与最优铅门大小(y)存在一定的关系,最终拟合得到函数方程:y=-0.0033x2+0.7132x+3.6322。结论宫颈癌术后患者靶区横向宽度和最优铅门大小之间存在定量函数变化关系,可将其应用于临床,以指导宫颈癌术后患者容积调强计划设计。
Objective To summarize the relationship between the transverse dimension of the target volume and the most optimized X jaw size in volumetric modulated arc therapy( VMAT) plan for cervical cancer radiotherapy. Methods The VMAT plans were made by modifying X jaw size on CT images in 12 postoperative patients with cervical cancer. On each image,the best X jaw size was identified. The relationship between the best X jaw size and the transverse width of planning target volume( PTV) was determined. Results The change in the transverse dimension of the target volume was accompanied with the changes of the optimized X jaw size. The relationship between X jaw size( y) and the PTV's transverse width( x) could be expressed as the following equation: y =- 0. 0033x2+ 0. 7132x + 3. 6322. Conclusions There is a relationship between X jaw size and PTV's transverse width,which can be used for the postoperative VMAT plan design in patients with cervical cancer.

关键词(KeyWords): 宫颈癌;容积调强;固定铅门;剂量学
cervical cancer;volumetric modulated arc therapy;fixed-jaw technique;dosimetry

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作者(Author): 庞廷田;杨波;刘楠;刘峡;邱杰;张福泉;
PANG Ting-tian;YANG Bo;LIU Nan;LIU Xia;QIU Jie;ZHANG Fu-quan;Department of Radiation Oncology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College;

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