协和医学杂志

2020, v.11(02) 127-129

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溶栓技术在ST段抬高型心肌梗死救治中的地位
The Status of Thrombolytic Therapy in Treatment of ST-segment Elevation Myocardial Infarction

沈珠军;
SHEN Zhu-jun;Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College;

摘要(Abstract):

急性ST段抬高型心肌梗死的再灌注治疗中,溶栓治疗作为解决这一血栓性疾病的治疗方式,仍应具有相当重要的地位。近些年溶栓治疗用于心肌梗死治疗的相关临床研究已分别证实:(1)在发病时间较早且介入开始时间可能延误较长(>2 h)的情况下考虑首选;(2)在拟采取介入治疗但因有一些延误时(1 h)考虑使用低剂量溶栓药物辅助溶栓后再行介入治疗;(3)在冠状动脉内血栓负荷严重时冠状动脉内使用溶栓药物再行介入治疗,以上3种情况临床应用时应予以充分考虑。
Thrombolytic revascularization therapy still remains an important method in the treatment of ST-segment elevation myocardial infarction(STEMI). Recent clinical studies confirmed the status of thrombolytic therapy in 3 clinical situations: estimated long delay(>2 hours) in primary percutaneous coronary intervention(PCI), pharmco-invasive thrombolytic therapy with estimated PCI delay(1 hour), a large thrombus treated with intra-coronary use of low dose thrombolytic therapy during primary PCI. Above 3 conditions should be fully considered during clinical application.

关键词(KeyWords): ST段抬高型心肌梗死;溶栓治疗;介入治疗
ST-segment elevation myocardial infarction;thrombolytic therapy;interventional therapy

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作者(Author): 沈珠军;
SHEN Zhu-jun;Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College;

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