协和医学杂志

2018, v.9(05) 399-403

[打印本页] [关闭]
本期目录(Current Issue) | 过刊浏览(Past Issue) | 高级检索(Advanced Search)

感染性疾病病原学诊断新技术与临床应用策略
New Technology of Etiologic Diagnosis in Infectious Diseases and Its Clinical Application Strategy

张坚磊;马小军;
ZHANG Jian-lei;MA Xiao-jun;Department of Clinical Laboratory,Tianjin First Center Hospital;Department of Infectious Diseases,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences &Peking Union Medical College;

摘要(Abstract):

感染性疾病仍是威胁人类健康的主要疾病,传统诊断技术已无法满足临床需求,病原学诊断技术的发展对感染性疾病的诊断治疗至关重要。近年来,非培养的新型诊断技术正在迅速发展,特别是基于侧流免疫层析法和实时聚合酶链式反应为基础的即时检验,以及基于蛋白质组学质谱和高通量测序技术不断应用于临床,使感染性疾病的临床诊断向着更便捷、快速、准确的方向发展。但仍需正确对待新型诊断技术在临床应用中的问题,从循证医学角度评估诊断试验,关注应用人群,以最佳证据应用于合适人群以达到最佳效果,让病原学诊断新技术的应用真正解决临床诊断问题,最终为临床感染性疾病诊疗的科学决策提供依据。
Infectious diseases are still the main diseases that threaten human health. Traditional diagnostic technology has been unable to meet the clinical needs. The development of pathogenic diagnosis technology is of vital importance to the diagnosis and treatment of infectious diseases. In recent years,non-cultured new diagnostic technologies have been rapidly developing,especially the real-time detection based on lateral flow immunoassay and real-time polymerase chain reaction. The continuous application of proteomics mass-spectrometry and highthroughput sequencing technology in clinical practice makes the clinical diagnosis of infectious diseases more convenient,faster and more accurate. However,it is necessary to correctly handle the problems in the clinical application of new diagnostic technology. Diagnostic tests should be assessed from the angle of evidence-based medicine and the applied crowds to gather the best evidence,so that they can be applied to the appropriate people and achieve the best effect,making the application of new technology in etiologic diagnosis really solve the problem of clinical diagnosis and eventually provide the basis for scientific decision-making about the clinical diagnosis and treatment of infectious diseases.

关键词(KeyWords): 感染性疾病;诊断技术;循证医学
infectious diseases;diagnostic techniques;evidence-based medicine

Abstract:

Keywords:

基金项目(Foundation): 国家临床重点专科建设项目(2013-544)

作者(Author): 张坚磊;马小军;
ZHANG Jian-lei;MA Xiao-jun;Department of Clinical Laboratory,Tianjin First Center Hospital;Department of Infectious Diseases,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences &Peking Union Medical College;

Email:

DOI:

参考文献(References):

扩展功能
本文信息
服务与反馈
本文关键词相关文章
本文作者相关文章
中国知网
分享