协和医学杂志

2019, v.10(01) 81-83

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抗菌药物管控刻不容缓
Urgent Need of Antimicrobial Stewardship

陈新飞;侯欣;肖盟;徐英春;
CHEN Xin-fei;HOU Xin;XIAO Meng;XU Ying-chun;Department of Clinical Laboratory,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences &Peking Union Medical College;Graduate School,Chinese Academy of Medical Sciences & Peking Union Medical College;Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Diseases;

摘要(Abstract):

细菌耐药已成为全球共同面临的严峻挑战。在我国,由于公众对抗菌药物的认识存在误区,抗菌药物不合理使用现象较为普遍,导致细菌耐药率升高,其中鲍曼不动杆菌对碳青霉烯类药物的耐药率已上升至71. 4%。面对如此严峻的形势,加强对抗菌药物的管控迫在眉睫。随着政府相关部门对细菌耐药问题的重视及合理使用抗菌药的观念渐入人心,细菌耐药状况得到部分改善,如肠杆菌科细菌对碳青霉烯类抗生素耐药性较稳定,大多<10%;耐甲氧西林金黄色葡萄球菌的检出率亦由69%降至38. 4%。未来仍需加强抗菌药物管控,继续采取有效措施,积极践行遏制细菌耐药行动,为实现健康中国的目标而奋斗。
Antimicrobial resistance has become a severe challenge worldwide. In China,due to misunderstanding the function of antimicrobials,antimicrobial drugs are abused by the public. The resistance rate of Acinetobacter baumannii to carbapenems has risen to 71. 4%. Facing such a severe problem,it is urgent to strengthen the control of antimicrobials. With the awareness and action of the government,this situation has partially improved. Rational use of antimicrobials is becoming more and more accepted by the public. The resistance rate of Enterobacteriaceae bacteria to carbapenems becomes stable,mostly <10%,and the rate of methicillin-resistant Staphylococcus aureus has greatly reduced from 69% to 38. 4%. But it is still necessary to strengthen the management of antimicrobials and take effective measures to prevent resistance and to achieve the grand goal of a healthy China.

关键词(KeyWords): 细菌耐药;管理措施
antimicrobial drug resistance;measures of control

Abstract:

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基金项目(Foundation): 北京协和医院中青年科研基金(pumch-2016-1.2)

作者(Author): 陈新飞;侯欣;肖盟;徐英春;
CHEN Xin-fei;HOU Xin;XIAO Meng;XU Ying-chun;Department of Clinical Laboratory,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences &Peking Union Medical College;Graduate School,Chinese Academy of Medical Sciences & Peking Union Medical College;Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Diseases;

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