盖小荣;莎仁高娃;
GAI Xiao-rong,Sharengaowa Department of Health Management,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College,Beijing 100730,China

• 1:中国医学科学院 北京协和医学院 北京协和医院健康医学部

摘要(Abstract)：

目的探讨健康体检人群甲状腺癌的发生率及其变化趋势。方法选取2009年1月至2011年6月北京协和医院10903名行甲状腺超声检查的健康体检人群,对高度怀疑甲状腺癌者建议手术切除,并分析甲状腺癌的发病情况。结果超声检查高度怀疑甲状腺癌54例,手术切除后病理证实甲状腺癌40例,甲状腺癌在健康体检人群的发病率为0.37%,其中男性为0.23%,女性为0.53%。结论甲状腺癌在人群中的发病率明显增高,女性尤为明显,需有针对性地采取预防措施。
Objective To investigate the incidence and tendency of thyroid carcinoma in adults during health check-up.Methods Sonogrphic assessment of thyroid was performed in 10 903 adults from January 2009 to June 2011 and surgical operations were performed for the suspected malignant tumors.The incidence of thyroid carcinoma was calculated.Results Of 54 highly suspected malignant tumors under ultrasound,40 were pathologically confirmed to be thyroid carcinoma,yielding an incidence of thyroid carcinoma of 0.37% among these health chech-up receivers (0.23% in male and 0.53% in female).Conclusion The incidence of thyroid carcinoma has remarkably increased,especially in females.Preventive efforts should be taken to address this trend.

关键词(KeyWords)： 甲状腺癌;超声检查;发病率
thyroid carcinoma;ultrasound examination;incidence

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 盖小荣;莎仁高娃;
GAI Xiao-rong,Sharengaowa Department of Health Management,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College,Beijing 100730,China

Email:

DOI:

参考文献(References)：

• [1]姜玉新,张波.甲状腺结节的超声诊断及治疗[J].协和医学杂志,2010,1:34-39.
• [2]Hedinger C,Williams ED,Sobin LH,et al.Histological typing of thyroid tumors[M]//WHO international histologi-cal classification of tumors.2nd ed.London:springer,1988:10-14.
• [3]钱碧云,何敏,董淑芬,等.1981年至2001年天津市甲状腺癌的发病率和死亡率[J].中华内分泌代谢杂志,2005,21:432-434.
• [4]Nix P,Nicolaides A,Coatesworth AP.Thyroid cancer review1:presentation and investigation of thyroid cancer[J].Int J Clin Pract,2005,59:1340-1344.
• [5]Papini E,Guglielmi R,Bianchini A,et al.Risk of malignancy in nonpalpable thyroid nodules:predictive value to ul-trasound and color-Doppler features[J].J Clin Endocrinol Metab,2002,87:1941-1946.
• [6]骆韵青,章燕锋,单桂英,等.甲状腺微小乳头状癌超声特征分析[J].中国临床医学影像杂志,2010,21:46-48.
• [7]龙丽娟,胡蓉,邵波,等.超声探测钙化灶在甲状腺结节诊断中的临床价值[J].中国医学影像学杂志,2009,17:286-287.
• [8]Jun P,Chow LC,Jeffrey RB.The sonographic features of papillary thyroid carcinomas:pictorial essay[J].Ultra-sound Q,2005,2:39-45.
• [9]陈杰,李甘地.病理学[M].北京:人民卫生出版社,2005:399.
• [10]Kono K,Inoue Y,Nakayama K,et al.The role of diffusion-weighted imaging in patients with brain tumnors[J].AJNR Am J Neuroradiol,2001,22:1081-1088.
• [11]Ilias I,Alevizaki M,Lakka PE.Differentiated thyroid cancer in Greece:1963-2000.Relation to demographic and en-vironmental factors[J].Hormones(Athens),2002,1:174-178.
• [12]Mishra AM,Gupta RK,Jaggi RS,et al.Role of diffusion-weighted imaging and in vivo proton magnetic resonance spectroscopy in the differential diagnosis of ring-enhancing intracranial cystic mass lesions[J].J Comput Assist To-mogr,2004,28:540-547.
• [13]Zhu QX,Bian JC,Shen Q,et al.Study of genetic effect on papillary thyroid carcinoma[J].Chin Prev Med,2004,7:125-129.
• [14]单忠艳,关海霞.甲状腺癌相关研究进展[J].中国实用内科杂志,2007,27:33-36.
• [15]Vivacqua A,Bonofiglio D,Albanito L,et al.17beta-es-tradiol,genistein,and4-hydrexytamoxifen induce the prolif-eration of thyroid cancer cells through the G protein-coupled receptor GPR30[J].Mol Pharmacol,2006,70:1414-1423.