肾细胞癌相关遗传性综合征
陈健;纪志刚;
摘要(Abstract):
<正>肾细胞癌是泌尿外科常见肿瘤,从遗传学角度可分为散发性肾细胞癌和遗传性肾细胞癌,有遗传基础的肾细胞癌占所有肾细胞癌的5%[1]。遗传性肾细胞癌多并发全身其他组织脏器良性病变或恶性肿瘤,故称为肾细胞癌相关遗传综合征,各种肾细胞癌相关遗传性综合征均具有不同的突变基因、临床表现及病理类型。以往对肾细胞癌相关遗传性综合征的描述主要基于临床观察,如疾病的外在表现和家族遗传特点;近年来家系研究和分子遗传学进展为了解肾细胞癌相
关键词(KeyWords):
肾细胞癌;遗传综合征
基金项目(Foundation):
作者(Author):
陈健;纪志刚;
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DOI:
参考文献(References):
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