协和医学杂志

2013, (04)

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螺旋断层调强技术的临床应用

刘志凯;杨波;胡克;侯晓荣;邱杰;张福泉

摘要(Abstract):

目的:分析总结北京协和医院放疗科应用螺旋断层调强放疗技术治疗多种良恶性肿瘤方面的初步经验。材料与方法:通过对前列腺癌、多发脑转移癌、生殖细胞瘤、乳腺癌、胰腺癌及侵袭性垂体瘤螺旋断层调强放疗方案的分析,总结螺旋断层调强放疗相比于传统加速器调强放疗的优势。结果:螺旋断层调强放疗在靶区均匀性及适形度、剂量分级给予、危及器官受量、射野衔接方面较传统加速器调强放疗具有优势。结论:螺旋断层调强放疗在治疗复杂靶区、超长靶区、瘤区同步加量及重要危及器官保护等方面具有比传统加速器明显的放射物理学优势,并可能提高疗效、降低副反应。螺旋断层调强放疗针对不同病种的临床优势尚需进一步研究。
Objective: To present the early experience of using TomoTherapy to treat a variety of benign and malignant tumors in radiotherapy department of PUMC hospital. Materials and Methods: We present treatment plans of TomoTherapy which had advantages over fixed field IMRT. The treatment plans were prostate cancer, multiple brain metastases, germ cell tumors, breast cancer, pancreatic cancer and invasive pituitary adenoma. Results: TomoTherapy had advantages on homogeneity and Conformity of target, different dose levels, protection of risk organs and radiation field convergence over fixed field IMRT. Conclusion: TomoTherapy had significant physical advantages over fixed field IMRT for complex and long target, simultaneous integrated boost of target and protection of risk organs. Clinical advantages of TomoTherapy need further study.

关键词(KeyWords): |螺旋断层调强放疗 同步加量|
|TomoTherapy| simultaneous integrated boost|

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作者(Author): 刘志凯;杨波;胡克;侯晓荣;邱杰;张福泉

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