协和医学杂志

2020, v.11(02) 186-190

[打印本页] [关闭]
本期目录(Current Issue) | 过刊浏览(Past Issue) | 高级检索(Advanced Search)

印记基因与小于胎龄儿研究进展
Imprinted Genes and Being Small for Gestational Age

潘周娴;陈适;朱惠娟;龚凤英;潘慧;
PAN Zhou-xian;CHEN Shi;ZHU Hui-juan;GONG Feng-ying;PAN Hui;Department of Allergy,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College;Department of Endocrinology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College;Department of Medical Affairs,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College;

摘要(Abstract):

基因组印记是令一对等位基因仅表达父源或母源基因的一种表观遗传性修饰,多在胎盘中存在,对胎盘和胚胎发育至关重要。在对小于胎龄儿发病机制的研究中,印记基因是不可缺少的一部分。但相关研究争议很大,尚未得出统一的结论。本文就近些年印记基因与小于胎龄儿的研究予以综述。
Imprinted genes are epigenetic modifications that make a pair of alleles express only paternal or maternal genes. Most of the imprinted genes exist in the placenta and are very important for placental and embryonic development. Imprinted genes are an indispensable part of the study of the pathogenesis of being small for gestational age. However, relevant research is controversial and has not yet reached a common conclusion. In this paper, recent studies on the relation ofimprinted genes and being small for gestational age are reviewed.

关键词(KeyWords): 印记基因;小于胎龄儿
imprinted genes;small for gestational age

Abstract:

Keywords:

基金项目(Foundation): 北京市卫生科技成果与适宜技术推广项目(2018-TG-35)

作者(Author): 潘周娴;陈适;朱惠娟;龚凤英;潘慧;
PAN Zhou-xian;CHEN Shi;ZHU Hui-juan;GONG Feng-ying;PAN Hui;Department of Allergy,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College;Department of Endocrinology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College;Department of Medical Affairs,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College;

Email:

DOI:

参考文献(References):

扩展功能
本文信息
服务与反馈
本文关键词相关文章
本文作者相关文章
中国知网
分享