协和医学杂志

2012, (04)

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近视眼儿童与成人角膜地形图的比较和相关分析
Comparison and Correlation Analysis of Corneal Topography in Myopic Children and Adults

艾凤荣;金玉梅;李莹;张玥

摘要(Abstract):

目的:比较儿童和成人近视眼患者的角膜地形图的形态特点,并分析角膜地形图参数与年龄和屈光度的相关性。方法:2008 年8月至2010 年8月北京协和医院儿童和成人近视眼患者各100例200眼,分别进行角膜地形图的测量及屈光度的检查。结果:成人组角膜地形图参数中平坦子午线角膜屈光力(K2)、角膜表面规则指数(surface regularity index, SRI)、角膜表面非对称指数 (surface asymmetry index, SAI)值均显著高于儿童组(P<0.05),而陡峭子午线角膜屈光力(K1)、最小角膜屈光力子午线(minK)与儿童组相比较差异无统计学意义(P>0.05)。两组参数在不同性别间比较,女性K1、K2及minK均显著高于男性(P<0.05);而SRI、SAI差异均无统计学意义(P>0.05)。成人组SRI、SAI与年龄有明显相关性(SRI:r=0.20,P<0.05;SAI:r=0.19,P<0.05),而儿童组与年龄无相关性(P>0.05);但SRI、SAI与两组的屈光度均无相关性(P>0.05)。两组的角膜中央图形均以蝴蝶结形为主;角膜散光轴位大多表现为循规性散光。结论:随着年龄增长,屈光度的增加,角膜表面不规则、不对称指数等角膜形态会发生某种程度的变化,散光轴位趋向于垂直方向。
Objective To investigate and analyze the morphological characteristics of corneal topography in pediatric and adult patients with myopia. Methods Topographic measurement and refractive examination were performed respectively on 200 eyes of 100 pediatric and adult patients with myopia admitted to Peking Union Medical College Hospital from August 2008 to August 2010. Results The values of flat keratometric power (K2,) surface regularity index (SRI), and surface asymmetry index (SAI) in myopic adults were significantly higher than those in myopic children (P<0.05). However, the values of steep keratometric power (K1) and minimum keratometric power (minK) showed no such difference between these two groups (P>0.05). Furthermore, comparison of these parameters between males and females in both two groups showed the values of K1, K2 and minK in females were significantly higher than in males (P<0.05). The SRI and SAI in adult group were significantly correlated with age (SRI: r=0.20, P<0.05; SAI: r=0.19, P<0.05), no such correlation was found in children group(P>0.05). There were no correlation between SRI or SAI and refraction in both two groups (P>0.05). The central cornea showed bow-type graphics mostly in two groups. Most of the astigmatism was with the rule. Conclusion With the increase of age, the refraction, corneal surface irregularities, and asymmetry index shows certain changes, whereas the axis of astigmatism tends to be vertical.

关键词(KeyWords): |近视|角膜地形图|角膜形态|
|myopia| corneal topography| corneal shape|

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作者(Author): 艾凤荣;金玉梅;李莹;张玥

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