协和医学杂志

2020, v.11(02) 213-217

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综合医院院级平台化样本库各类分库效能的比较
Comparisons of the Efficiency of Different Hospital-level Platform-based Sub-Biobanks in General Hospital

陈奕霖;魏巍;李秀红;张璇;黄涛;张平;张允;
CHEN Yi-lin;WEI Wei;LI Xiu-hong;ZHANG Xuan;HUANG Tao;ZHANG Ping;ZHANG Yun;Clinical Data and Biobank Resource,Research Center,Beijing Friendship Hospital,Capital Medical University;Clinical Epidemiology and Evidence-based Medical Center,Beijing Friendship Hospital,Capital Medical University;

摘要(Abstract):

目的提出综合医院平台化样本库各分库表现的评价方法,并对各分库的综合表现进行评估,以期为从事样本库建设的同仁提供参考。方法将北京友谊医院2014年10月1日至2018年3月31日期间建立的所有样本分库纳入本研究。采用样本入库、样本应用以及样本质量3项指标进行分析评价,并将上述3项指标赋予不同权重进行综合评估(样本入库30%、样本应用30%、样本质量40%)。结果 77个样本分库中,项目库22个,储备库55个。入库评分方面,项目库和储备库差异无统计学意义(50.7±30.1比47.6±29.9,P=0.1614);应用评分、样本质量评分以及综合评分方面,项目库均显著高于储备库[应用评分:30.3(0,84.2)比0(0,31.6),P=0.0327;质量评分:100.0±0.0比94.5±22.9,P=0.0444;综合评分:62.5±14.8比57.9±17.9,P=0.0077]。结论综合医院院级平台化样本库中项目库的综合表现优于储备库。
Objective The aim of this study was to present a method for evaluating the comprehensive performance of each platform-based sub-Biobanks of a general hospital in order to provide reasonable advice to new Biobankers. Methods We conducted a comprehensive analysis of all these sub-Biobanks from three aspects including specimen incoming, specimen application, and specimen quality as well.We gave different weight of these 3 indicators for comprehensive evaluation(30% for incoming,30% for application,and 40% for quality). Results A total of 77 sub-Biobanks were included in this study, with 22 project-based Biobanks and 55 reserve Biobanks. There was no significant difference in specimen incoming scores between project-based banks and reserve banks(50.7±30.1 vs. 47.6±29.9, P=0.1614). Project-based Biobanks scored significantly better than reserve Biobanks in specimen application[30.3(0,84.2) vs. 0(0,31.6), P=0.0327], specimen quality(100.0±0.0 vs. 94.5±22.9, P=0.0444),and comprehensive score(62.5±14.8 vs. 57.9±17.9, P=0.0077). Conclusion Project-based Biobanks' comprehensive performance isbetter than that of reserve Biobanks in platform-based Biobanks of general hospitals.

关键词(KeyWords): 综合医院;平台化;院级样本库;评价体系
general hospital;platform-based;hospital-level Biobank;evaluation system

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基金项目(Foundation): 北京市医院管理局消化内科协同发展中心协同创新支撑体系建设消化系统临床样本资源网络建设与协同发展研究(XXX0103)

作者(Author): 陈奕霖;魏巍;李秀红;张璇;黄涛;张平;张允;
CHEN Yi-lin;WEI Wei;LI Xiu-hong;ZHANG Xuan;HUANG Tao;ZHANG Ping;ZHANG Yun;Clinical Data and Biobank Resource,Research Center,Beijing Friendship Hospital,Capital Medical University;Clinical Epidemiology and Evidence-based Medical Center,Beijing Friendship Hospital,Capital Medical University;

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