急诊“危险性”出血的合理用血
张放;郭树彬;
摘要(Abstract):
<正>急诊"危险性"出血是急性贫血最常见的病因,大量急性失血使机体在短时间内血红细胞(red blood cell,RBC)和血红蛋白(hemoglobin,Hb)含量急剧下降,低于正常值,无法满足机体对于血液和氧气的需要,其不仅包括创伤和疾病所致的血管性出血,亦包括合并严重基础疾病或出凝血功能异常所致的急性出血。急诊"危险性"出血具有临床发病急、出血量大、致死率高的特点,是急诊医生需要
关键词(KeyWords):
危险性出血,急诊;输血
基金项目(Foundation):
作者(Author):
张放;郭树彬;
Email:
DOI:
参考文献(References):
- [1]Simmons JW,Pittet JF,Pierce B.Trauma-induced coagulopathy[J].Curr Anesthesiol Rep,2014,4:189-199.
- [2]Cothren CC,Moore EE,Hedegaard HB,et al.Epidemiology of urban trauma deaths:a comprehensive reassessment 10years later[J].World J Surg,2007,31:1507-1511.
- [3]Gosselin RA,Spiegel DA,Coughlin R,et al.Injuries:the neglected burden in developing countries[J].Bull World Health Organ,2009,87:246-246a.
- [4]Loforte A,Marinelli G,Musumeci F,et al.Extracorporeal membrane oxygenation support in refractory cardiogenic shock:treatment strategies and analysis of risk factors[J].Artif Organs,2014,38:E129-E141.
- [5]Wilson DK,Polito CC,Haber MJ,et al.Patient factors associated with identification of sepsis in the ED[J].Am J Emerg Med,2014,32:1280-1281.
- [6]中国医师协会急诊医师分会.急诊临床紧急输血预案[J].中国急救医学,2013,33:673-675.
- [7]Takei T,Amin NA,Schmid G,et al.Progress in global blood safety for HIV[J].J Acquir Immune Defic Syndr,2009,52 Suppl 2:S127-S131.
- [8]Carson JL,Grossman BJ,Kleinman S,et al.Red blood cell transfusion:a clinical practice guideline from the AABB[J].Ann Intern Med,2012,157:49-58.
- [9]Kaufman RM,Djulbegovic B,Gernsheimer T,et al.Platelet transfusion:a clinical practice guideline from the AABB[J].Ann Intern Med,2015,162:205-213.
- [10]Nahirniak S,Slichter SJ,Tanael S,et al.Guidance on platelet transfusion for patients with hypoproliferative thrombocytopenia[J].Transfus Med Rev,2015,29:3-13.
- [11]Spahn DR,Bouillon B,Cerny V,et al.Management of bleeding and coagulopathy following major trauma:an updated European guideline[J].Crit Care,2013,17:R76.
- [12]Cap A,Hunt B.Acute traumatic coagulopathy[J].Curr Opin Crit Care,2014,20:638-645.
- [13]Frith D,Goslings JC,Gaarder C,et al.Definition and drivers of acute traumatic coagulopathy:clinical and experimental investigations[J].J Thromb Haemost,2010,8:1919-1925.
- [14]Mac Leod JB,Lynn M,Mc Kenney MG,et al.Early coagulopathy predicts mortality in trauma[J].J Trauma,2003,55:39-44.
- [15]CRASH-2trial collaborators,Shakur H,Roberts I,et al.Effects of tranexamic acid on death,vascular occlusive events,and blood transfusion in trauma patients with significant haemorrhage(CRASH-2):a randomised,placebo-controlled trial[J].Lancet,2010,376:23-32.
- [16]Ho AM,Dion PW,Yeung JH,et al.Prevalence of survivor bias in observational studies on fresh frozen plasma:erythrocyte ratios in trauma requiring massive transfusion[J].Anes-thesiology,2012,116:716-728.
- [17]Duggan J.Transfusion in gastrointestinal haemorrhage:time to change?[J].Intern Med J,2014,44:427-428.
- [18]Villanueva C,Colomo A,Bosch A,et al.Transfusion strategies for acute upper gastrointestinal bleeding[J].N Engl J Med,2013,368:11-21.
- [19]Northup PG,Caldwell SH.Coagulation in liver disease:a guide for the clinician[J].Clin Gastroenterol Hepatol,2013,11:1064-1074.
- [20]Turan A,Yang D,Bonilla A,et al.Morbidity and mortality after massive transfusion in patients undergoing non-cardiac surgery[J].Can J Anaesth,2013,60:761-770.