陈雯琳;王雅宁;邢浩;梁庭毓;石易鑫;王海;杨蕙钰;刘千舒;李俊霖;郭晓鹏;王裕;马文斌;
CHEN Wenlin;WANG Yaning;XING Hao;LIANG Tingyu;SHI Yixin;WANG Hai;YANG Huiyu;LIU Qianshu;LI Junlin;GUO Xiaopeng;WANG Yu;MA Wenbin;Department of Neurosurgery,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences &Peking Union Medical College;

• 1:中国医学科学院北京协和医院神经外科

摘要(Abstract)：

脑胶质瘤为发病率最高的中枢神经系统原发性恶性肿瘤，恶性程度高，患者预后差。目前，脑胶质瘤领域的研究主要聚焦于肿瘤发生机制探究、新治疗手段及药物研发方面，在胶质瘤分子病理分型优化、影像检查诊断技术提升及综合治疗指南制订方面亦开展了深入研究。本文将对2021年度我国脑胶质瘤领域的研究成果及重要进展进行阐述，并对未来可能的研究方向进行展望，以期为临床研究提供借鉴和参考。
Glioma, the most prevalent primary malignant tumor of the central nervous system, has a high degree of malignancy and poor prognosis for patients. At present, the researches of glioma mainly focus on the investigation of the mechanism of tumor occurrence and the discovery of new therapeutic methods and agents. In-depth researches have also been conducted on the optimization of molecular pathological typing of glioma, improvement of diagnostic imaging techniques and formulation of comprehensive treatment guidelines. In this review, we summarize the achievements and important progress made by Chinese medical scientists in the field of glioma in 2021,and propose possible future research directions with the aim of providing reference for clinical research.

关键词(KeyWords)： 胶质瘤;磁共振成像;替莫唑胺;靶向治疗;免疫微环境
glioma;magnetic resonance imaging;temozolomide;targeted therapy;immune microenvironment

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金(82151302);; 北京市自然科学基金[7202150,19JCZDJC64200(Z)];; 清华大学-北京协和医院合作课题(2019ZLH101)~~

作者(Authors): 陈雯琳;王雅宁;邢浩;梁庭毓;石易鑫;王海;杨蕙钰;刘千舒;李俊霖;郭晓鹏;王裕;马文斌;
CHEN Wenlin;WANG Yaning;XING Hao;LIANG Tingyu;SHI Yixin;WANG Hai;YANG Huiyu;LIU Qianshu;LI Junlin;GUO Xiaopeng;WANG Yu;MA Wenbin;Department of Neurosurgery,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences &Peking Union Medical College;

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