协和医学杂志

2020, (06) 754-757

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我国临床生物样本库平台化建设
Characteristics and Development of Platform Construction of Clinical Biobank in China

黄平;冯变莹;穆迪;周浩;姚祖德;满秋红;
HUANG Ping;FENG Bian-ying;MU Di;ZHOU Hao;YAO Zu-de;MAN Qiu-hong;Department of Clinical Laboratory,Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine;

摘要(Abstract):

医学研究迫切需要大量有价值的生物样本和数据资源集成共享来破解重大疾病难题。在医疗实践和医学研究过程中,临床生物样本库发挥了科研服务支撑平台作用,通过整合有限的生物样本与数据资源,为探索疾病发生、发展、转归、诊断、治疗及药物研发和健康预防等提供资源保障。本文着重阐述我国临床生物样本库平台标准化建设特点与发展、公共管理平台运行模式、信息化平台与资源平台运行管理及质量控制,以期推动我国临床生物样本库平台化、标准化建设。
Medical research urgently needs to integrate and share a large number of valuable biological samples and data resources to solve difficult problems in major diseases. In medical institutions, the clinical biological sample database plays the role of service-supporting platform for scientific research, which integrates limited biological samples and corresponding data to provide resource guarantee for the exploration of disease occurrence, development, transition, diagnosis, treatment, drug development and health prevention. In this paper, the characteristics and contents of standardized construction of clinical biobank platforms in China, the collaborative management mode of public management platforms, and the operation content and quality control of resource platforms were emphatically expounded. The purpose of this paper is to promote the standardized system construction of platforms of clinical biological sample database in China.

关键词(KeyWords): 临床生物样本库;平台;运行;质量控制
clinical biobank;platform;operation;quality control

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基金项目(Foundation): 国家重大研发计划(2016YFF0202301)

作者(Author): 黄平;冯变莹;穆迪;周浩;姚祖德;满秋红;
HUANG Ping;FENG Bian-ying;MU Di;ZHOU Hao;YAO Zu-de;MAN Qiu-hong;Department of Clinical Laboratory,Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine;

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