协和医学杂志

2016, (04)

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儿童单纯口服咪达唑仑的药代动力学

侯雪莹;万阔

摘要(Abstract):

咪达唑仑是一种安全快速的镇静药物,因其口服方式便捷有效而广泛应用于小儿临床。服药儿童年龄、药物剂型、剂量等均会影响咪达唑仑在体内的药代动力进而影响镇静效果,本文就小儿单纯口服咪达唑仑药代动力学研究进展做一综述,为临床用药提供参考。
Midazolam is a safe ,rapid sedative drug widely used in pediatrics for its convenient and effective way of oral administration. Age , dosage forms and doses etc can affect the dynamics of midazolam in the body , which further influence the sedative effect . The aim of this review is to summarize the pharmacokinetic characteristics of midazolam and relationship with the sedative effect in pediatrics , providing reference for clinical medication.

关键词(KeyWords): |咪达唑仑|口服|小儿科|药代动力学|

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作者(Author): 侯雪莹;万阔

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