协和医学杂志

2017, v.8(Z2) 274-277

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多部位病理证实的IgG4相关性疾病一例
A Case of IgG4-related Disease Confirmed by Pathology with Multiple Lesions

汪劭婷;孙雪峰;
WANG Shao-ting;SUN Xue-feng;Department of respiratory medicine,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences &Peking Union Medical College;

摘要(Abstract):

IgG4相关性疾病(IgG4-related disease,IgG4-RD)是累及多器官或组织的慢性进行性自身免疫性疾病,其病理为受累脏器被淋巴细胞和IgG4阳性的浆细胞浸润,肺部表现多样。本文报道了一例以咳嗽、气短起病的IgG4-RD,有肺、纵膈淋巴结、左颌下淋巴结、腹膜后、脾门、胃粘膜、皮肤受累,其肺野内病变表现为弥漫微结节,激素治疗后完全消失。
IgG4-related disease( IgG4-RD) is a chronic autoimmune disease implicating multiple organs and tissues. Its pathological characteristics are infiltration of lymphocytes and IgG4-positive plasma cells in the implicated organs. Pulmonary involvement reportedly varies. Here we reported a case of IgG4-RD with the onset of cough and dyspnea,presenting with multiple lesions. The pulmonary involvement was manifested as diffuse nodules in lungs that dissolved after glucocorticoid therapy.

关键词(KeyWords): IgG4相关性疾病;肺内结节;糖皮质激素
IgG4-related disease;pulmonary nodule;glucocorticoid

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作者(Author): 汪劭婷;孙雪峰;
WANG Shao-ting;SUN Xue-feng;Department of respiratory medicine,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences &Peking Union Medical College;

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