协和医学杂志

2020, v.11(04) 395-401

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原发性甲状旁腺功能亢进症诊断及手术治疗进展
Advances in Diagnosis and Surgical Treatment of Primary Hyperparathyroidism

崔铭;王鸥;廖泉;
CUI Ming;WANG Ou;LIAO Quan;Department of General Surgery, Peking Union Medical College Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College;Department of Endocrinology, Peking Union Medical College Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College;Department of General Surgery, Peking Union Medical College Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College;

摘要(Abstract):

原发性甲状旁腺功能亢进症(primary hyperparathyroidism, PHPT)是引起高钙血症的最常见病因,由一个或多个甲状旁腺病理性过量分泌甲状旁腺激素(parathyroid hormone, PTH)所致。随着血钙及PTH检查的普及,PHPT的发病率明显增加,成为影响人类健康的常见内分泌疾病,其诊治理念也在不断更新。绝大多数PHPT为散发性,约5%~10%的病例以遗传性PHPT的形式发病。本文讨论PHPT的诊断及手术治疗进展,以期为临床提供借鉴。
Primary hyperparathyroidism(PHPT) is the most common cause of hypercalcemia, which is due to excessive secretion of parathyroid hormone(PTH) from one or several parathyroid glands. With the tests of serum calcium and PTH being routinely employed, the incidence of PHPT has distinctly increased and PHPT has become a common endocrine disorder. The concept of diagnosis and treatment for PHPT has been developing continuously. Most cases of PHPT are sporadic, while 5%-10% of cases are hereditary. In this literature, we reviewed the advances in diagnosis and surgical treatment of PHPT.

关键词(KeyWords): 原发性甲状旁腺功能亢进症;遗传性疾病;诊断;手术治疗
primary hyperparathyroidism;hereditary disease;diagnosis;surgical treatment

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基金项目(Foundation): 中国医学科学院医学与健康科技创新工程(2017-I2M-1-001)

作者(Author): 崔铭;王鸥;廖泉;
CUI Ming;WANG Ou;LIAO Quan;Department of General Surgery, Peking Union Medical College Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College;Department of Endocrinology, Peking Union Medical College Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College;Department of General Surgery, Peking Union Medical College Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College;

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