杨荣利;陈秀凯;王小亭;刘大为;
YANG Rong-li;CHEN Xiu-kai;WANG Xiao-ting;LIU Da-wei;Department of Critical Care Medicine,Dalian Municipal Central Hospital affiliated of Dalian Medical University;Department of Critical Care Medicine,University of Pittsburgh School of Medicine;Department of Microbiology and Molecular Genetics,University of Pittsburgh School of Medicine;Department of Critical Care Medicine,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences &Peking Union Medical College;

• 1:大连医科大学附属大连市中心医院重症医学科
• 2:匹兹堡大学医学院
• 3:匹兹堡大学医学院微生物与分子基因学系
• 4:中国医学科学院北京协和医学院北京协和医院重症医学科

摘要(Abstract)：

重症血液净化学是在重症医学理论指导下,研究机体内环境与重症相关性及变化规律,并运用血液净化技术治疗重症的科学。重症患者病情的复杂多变性,决定了重症血液净化的方式需灵活选用不同血液净化技术,因而表现出集成的特点。其具体形式包括序贯集成和同步集成。本文详细阐述了重症血液净化的集成特征和主要集成技术。
The discipline of critical care blood purification( CCBP) is a branch of science that aims at studying changes of the internal environment in critically ill patients and relating principles,and exploring the methodology of blood purification with the guidance of theories of critical care medicine. Because of the complexity and variability of the conditions of critically ill patients,we should select different blood purification techniques according to the state of the illness,which makes integration as one of main characteristics of CCBP. There are two forms of integration: sequential integration and concurrent integration. This article will elaborate on the integration feature and main integration techniques of CCBP.

关键词(KeyWords)： 重症血液净化;集成
critical care blood purification;integration

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 杨荣利;陈秀凯;王小亭;刘大为;
YANG Rong-li;CHEN Xiu-kai;WANG Xiao-ting;LIU Da-wei;Department of Critical Care Medicine,Dalian Municipal Central Hospital affiliated of Dalian Medical University;Department of Critical Care Medicine,University of Pittsburgh School of Medicine;Department of Microbiology and Molecular Genetics,University of Pittsburgh School of Medicine;Department of Critical Care Medicine,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences &Peking Union Medical College;

Email:

DOI:

参考文献(References)：

• [1]杨荣利,李素玮,陈秀凯,等.重症血液净化:从技术到科学[J].中华医学杂志,2017,97:2241-2263.
• [2]杨荣利,陈秀凯,王小亭,等.重症血液净化:从连续肾脏替代治疗到集成技术[J].中华医学杂志,2013,93:2769-2771.
• [3]Cheng J,Hu S,Lu H,et al.Comparison of the therapeutic effectiveness of sustained low-efficiency dialysis(SLED)with continuous blood purification(CBP)in critically ill patients[J].Cell Biochem Biophys,2013,67:923-927.
• [4]Parakininkas D,Greenbaum LA.Comparison of solute clearance in three modes of continuous renal replacement therapy[J].Pediatr Crit Care Med,2004,5:269-274.
• [5]Ponce D,Abrao JM,Albino BB,et al.Extended daily dialysis in acute kidney injury patients:metabolic and fluid control and risk factors for death[J].PLo S One,2013,8:e81697.
• [6]Komura T,Taniguchi T,Sakai Y,et al.Efficacy of continuous plasma diafiltration therapy in critical patients with acute liver failure[J].J Gastroenterol Hepatol,2014,29:782-786.
• [7]Mori T,Eguchi Y,Shimizu T,et al.A case of acute hepatic insufficiency treated with novel plasmapheresis plasma diafiltration for bridge use until liver transplantation[J].Ther Apher,2002,6:463-466.
• [8]Lumlertgul D,Suteeka Y,Tumpong S,et al.Double filtration plasmapheresis in different diseases in Thailand[J].Ther Apher Dial,2013,17:99-116.
• [9]Ronco C,Brendolan A,Lonnemann G,et al.A pilot study of coupled plasma filtration with adsorption in septic shock[J].Crit Care Med,2002,30:1250-1255.
• [10]Hassan J,Cader RA,Kong NC,et al.Coupled plasma filtration adsorption(CPFA)plus continuous veno-venous haemofiltration(CVVH)versus CVVH alone as an adjunctive therapy in the treatment of sepsis[J].EXCLI J,2013,12:681-692.